Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Qi Zhou
PROVIDER: E-GEOD-21515 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
The Journal of biological chemistry 20100409 25
Low reprogramming efficiency and reduced pluripotency have been the two major obstacles in induced pluripotent stem (iPS) cell research. An effective and quick method to assess the pluripotency levels of iPS cells at early stages would significantly increase the success rate of iPS cell generation and promote its applications. We have identified a conserved imprinted region of the mouse genome, the Dlk1-Dio3 region, which was activated in fully pluripotent mouse stem cells but repressed in parti ...[more]