FN1 expression is a marker of radioresistance in head and neck squamous cell carcinoma
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Roland Grafström
PROVIDER: E-GEOD-21644 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma.
Jerhammar Fredrik F Ceder Rebecca R Garvin Stina S Grénman Reidar R Grafström Roland C RC Roberg Karin K
Cancer biology & therapy 20101215 12
Radiotherapy remains the backbone of head and neck cancer therapy but response is sometimes impeded by tumor radioresistance. Identifying predictive biomarkers of radiotherapy response is a crucial step towards personalized therapy. The aim of this study was to explore gene expression data in search of biomarkers predictive of the response to radiotherapy in head and neck squamous cell carcinoma (HNSCC). Microarray analysis was performed on five cell lines with various intrinsic radiosensitivity ...[more]
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