Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Francesca Buffa
PROVIDER: E-GEOD-22219 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Buffa Francesca M FM Camps Carme C Winchester Laura L Snell Cameron E CE Gee Harriet E HE Sheldon Helen H Taylor Marian M Harris Adrian L AL Ragoussis Jiannis J
Cancer research 20110707 17
microRNA expression profiling plays an emerging role in cancer classification and identification of therapeutic strategies. In this study, we have evaluated the benefits of a joint microRNA-mRNA analysis in breast cancer. Matched mRNA and microRNA global expression profiling was conducted in a well-annotated cohort of 207 cases with complete 10-year follow-up. Penalized Cox regression including microRNA expression, mRNA expression, and clinical covariates was used to identify microRNAs associate ...[more]