Genomics

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MicroRNA expression profiling of early primary breast cancer to identify prognostic markers and associated pathways


ABSTRACT: Retrospective series of primary breast cancer patients who received surgery between 1989 and 1992. Patients received adjuvant chemotherapy and/or adjuvant hormone therapy, or no adjuvant treatment. Tamoxifen was used as endocrine therapy for 5 years in ER+ BC patients. Patients who were <50 years of age, with lymph node positive tumors, or ER– and/or >3 cm in diameter, received adjuvant cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) for six cycles, in a thrice weekly intravenous regimen. Patients >50 years of age with ER–, lymph node–positive tumors also received CMF.

ORGANISM(S): Homo sapiens

PROVIDER: GSE22216 | GEO | 2011/07/08

SECONDARY ACCESSION(S): PRJNA129183

REPOSITORIES: GEO

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