Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Lesleyann Hawthorn
PROVIDER: E-GEOD-22840 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hawthorn Lesleyann L Luce Jesse J Stein Leighton L Rothschild Jenniffer J
BMC cancer 20100827
<h4>Background</h4>A major challenge in the interpretation of genomic profiling data generated from breast cancer samples is the identification of driver genes as distinct from bystander genes which do not impact tumorigenesis. One way to assess the relative importance of alterations in the transcriptome profile is to combine parallel analyses that assess changes in the copy number alterations (CNAs). This integrated analysis permits the identification of genes with altered expression that map w ...[more]