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Expression of 50-500nt ncRNAs in silkworm Bombyx mori during two developmental transitions

ABSTRACT: We have performed the first systematic identification and analysis of intermediate size ncRNAs (50-500 nt) in the silkworm genome. We identified 194 novel ncRNAs, the expression profiles of them during the transitions from the egg to the first instar larva and from the fifth instar larva to the pupa were anlyzed by dual-channel microarray. Results showed that 12 ncRNAs had significantly differential expression during the two developmental transitions. The first instar larva sample was used for comparison to the sample of embryo, the fifth instar larva sample was used for comparison to the sample of pupa, respectively.

ORGANISM(S): Bombyx mori

SUBMITTER: Yunchao Kan 

PROVIDER: E-GEOD-22912 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Experimental RNomics and genomic comparative analysis reveal a large group of species-specific small non-message RNAs in the silkworm Bombyx mori.

Li Dandan D   Wang Yanhong Y   Zhang Kun K   Jiao Zhujin Z   Zhu Xiaopeng X   Skogerboe Geir G   Guo Xiangqian X   Chinnusamy Viswanathan V   Bi Lijun L   Huang Yongping Y   Dong Shuanglin S   Chen Runsheng R   Kan Yunchao Y  

Nucleic acids research 20110111 9

Accumulating evidences show that small non-protein coding RNAs (ncRNAs) play important roles in development, stress response and other cellular processes. The silkworm is an important model for studies on insect genetics and control of lepidopterous pests. Here, we have performed the first systematic identification and analysis of intermediate size ncRNAs (50-500 nt) in the silkworm. We identified 189 novel ncRNAs, including 141 snoRNAs, six snRNAs, three tRNAs, one SRP and 38 unclassified ncRNA  ...[more]

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