Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of rat kidney samples from normal and acute hypotensive animals

ABSTRACT: Rat kidney in normo- and hypotensive animals.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Timm Westhoff 

PROVIDER: E-GEOD-2401 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A physiogenomic approach to study the regulation of blood pressure.

Westhoff Timm H TH   Scheid Stefanie S   Tölle Markus M   Kaynak Bogac B   Schmidt Sven S   Zidek Walter W   Sperling Silke S   van der Giet Markus M  

Physiological genomics 20050607 1

Several vasoregulatory systems including the renin-angiotensin system, sympathetic vasoregulation, and cytokine release have been studied extensively. The aim of the present study was to establish a physiogenomic screening model for differentially expressed genes in the regulation of blood pressure that might give a hint as to new vasoregulatory mechanisms. We induced acute hypotension in normotensive rats, assuming that vasoregulatory systems will counteract hypotension. Microarray transcriptom  ...[more]

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