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Expression data for PAR-1-positive and -negative melanoma cell lines

ABSTRACT: PAR-1 is known to be involved in the transition from non-metastatic to metastatic melanoma. We sought to determine the downstream target genes regulated by PAR-1 to determine how PAR-1 is contributing to the metastatic melanoma phenotype. The A375SM metastatic melanoma cell line was subjected to stable transduction of lentiviral-delivered small hairpin RNA (shRNA) targeting PAR-1. As a control, a non-targeting shRNA sequence (no homology to any human gene) was also transduced into A375SM cells.

ORGANISM(S): Homo sapiens

SUBMITTER: Gabriel Villares

PROVIDER: E-GEOD-24259 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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