Effects of fescue toxicosis on rat hepatic tissue
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Raja Settivari
PROVIDER: E-GEOD-2452 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Genomic analysis of the impact of fescue toxicosis on hepatic function.
Settivari R S RS Bhusari S S Evans T T Eichen P A PA Hearne L B LB Antoniou E E Spiers D E DE
Journal of animal science 20060501 5
Fescue toxicosis is caused by consumption of toxins produced by an endophytic fungus, Neotyphodium coenophialum, in tall fescue [Lolium arundinaceum (Schreb.) Darbysh]. Microarray analysis was used to identify shifts in genetic expression associated with the affected physiological processes to identify potential targets for future pharmacological/toxicological intervention. Male rats (n = 24) were implanted with temperature transmitters, which measure core temperature every 5 min. After an 8-d r ...[more]
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