Expression and SNP array data for oral squamous cell carcinoma
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ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Chien-Hua Peng
PROVIDER: E-GEOD-25104 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma.
Peng Chien-Hua CH Liao Chun-Ta CT Peng Shih-Chi SC Chen Yin-Ju YJ Cheng Ann-Joy AJ Juang Jyh-Lyh JL Tsai Chi-Ying CY Chen Tse-Ching TC Chuang Yung-Jen YJ Tang Chuan-Yi CY Hsieh Wen-Ping WP Yen Tzu-Chen TC
PloS one 20110811 8
Molecular methods for predicting prognosis in patients with oral cavity squamous cell carcinoma (OSCC) are urgently needed, considering its high recurrence rate and tendency for metastasis. The present study investigated the genetic basis of variations in gene expression associated with poor prognosis in OSCC using Affymetrix SNP 6.0 and Affymetrix GeneChip Human Gene 1.0 ST arrays. We identified recurrent DNA amplifications scattered from 8q22.2 to 8q24.3 in 112 OSCC specimens. These amplicons ...[more]
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