Transcription profiling of pterygium and cornea
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yong Wee Wong
PROVIDER: E-GEOD-2513 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Expression of insulin-like growth factor binding protein-3 in pterygium tissue.
Wong Y W YW Chew J J Yang H H Tan D T H DT Beuerman R R
The British journal of ophthalmology 20060217 6
<h4>Background</h4>Pterygium is a fibrovascular overgrowth from the conjunctiva onto the cornea. The pathogenesis of this common ocular surface disorder is not well understood and the only treatment is surgical removal.<h4>Methods</h4>DNA microarray analysis of primary pterygium tissue was carried out using uninvolved conjunctiva tissue as a comparison for gene expression levels. Real time polymerase chain reaction (PCR) was used to verify the mRNA level of expression for genes changed in pteryg ...[more]
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