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Characterization of whole blood gene expression profiles of healthy miniature pigs with increasing age

ABSTRACT: Studying the causes and correlations of individual or age variation in gene expression is necessary for securing the reliability of the experimental animal. Feature of the blood gene expression of miniature pigs of fetus, 12, 20 and 30 weeks of age was examined. Gene expression in male and female miniature pigs was measured at fetus, 12, 20 and 30 weeks of age.

ORGANISM(S): Sus scrofa

SUBMITTER: Junko Takahashi

PROVIDER: E-GEOD-25393 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Oligonucleotide microarray analysis of age-related gene expression profiles in miniature pigs.

Takahashi Junko J Misawa Masaki M Iwahashi Hitoshi H

PloS one 20110513 5

Miniature pigs are useful model animals for humans because they have similar anatomy and digestive physiology to humans and are easy to breed and handle. In this study, whole blood microarray analyses were conducted to evaluate variations of correlation among individuals and ages using specific pathogen-free (SPF) Clawn miniature pigs. Whole blood RNA is easy to handle compared to isolated white blood cell RNA and can be used for health and disease monitoring and animal control. In addition, who ...[more]

PMID: 21603646

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