Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655
SUBMITTER: Bernhard Palsson
PROVIDER: E-GEOD-26589 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nucleic acids research 20110513 15
The PurR transcription factor plays a critical role in transcriptional regulation of purine metabolism in enterobacteria. Here, we elucidate the role of PurR under exogenous adenine stimulation at the genome-scale using high-resolution chromatin immunoprecipitation (ChIP)-chip and gene expression data obtained under in vivo conditions. Analysis of microarray data revealed that adenine stimulation led to changes in transcript level of about 10% of Escherichia coli genes, including the purine bios ...[more]