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Mechanisms of TGFB1 induced atrial fibrosis

ABSTRACT: This project aims to compare gene expression in transgenic mice that overexpress TGFB1 to wild type mice. Transgenic mice have a fibrotic response in the atria, but not the ventricle. This is a 2 color design; dye swaps and a loop design were incorporated. Each group has N=4, with the exception being WT atria which has N=3 and was hybridied twice, the groups are Wt atria, WT ventricle, Transgenic atria, Transgenic ventricle. Comparisons of interest : Tg atria vs WT atria, Tg ventricle vs WT ventricle, WT atria vs.dWT ventricle, Tg atria vs Tg ventricle

ORGANISM(S): Mus musculus

SUBMITTER: Andrea Barczak

PROVIDER: E-GEOD-27133 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Mechanisms of TGFB1 induced atrial fibrosis

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