Slf1p and Sro9p affinity isolations; SLF1 overexpression
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Andre Gerber
PROVIDER: E-GEOD-27312 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast.
Schenk Luca L Meinel Dominik M DM Strässer Katja K Gerber André P AP
RNA (New York, N.Y.) 20120123 3
The La-motif (LAM) is an ancient and ubiquitous RNA-binding domain defining a superfamily of proteins, which comprises the genuine La proteins and La-related proteins (LARPs). In contrast to La, which binds and stabilizes pre-tRNAs and other RNA polymerase III transcripts, data on function and RNA targets of the LARPs have remained scarce. We have undertaken a global approach to elucidate the previously suggested role of the yeast LARP Slf1p in copper homeostasis. By applying RNA-binding protein ...[more]
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