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Human subcutaneous adipose tissue and perithyroid adipose tissue gene expression

ABSTRACT: Different human adipose tissue depots may have functional differences. Subcutaneous human adipose tissue has been extensively studied, but less is known about other depots. Perithyroid (PT) adipose tissue contains not only white adipocytes but also brown adipocytes. The aim of this study was to compare the expression of brown adipocyte containing perithyroid adipose tissue with s.c. adipose tissue.role in the development of obesity. Expression profiling of adipose tissue may give insights into mechanisms contributing to obesity and obesity-related disorders. Expression analysis of paired biopsies from s.c and perithyriod (PT) adipose tissue from nine subjects undergoing surgery in the thyroid region.

ORGANISM(S): Homo sapiens

SUBMITTER: Per-Arne Svensson

PROVIDER: E-GEOD-27657 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Adipose tissue resting energy expenditure and expression of genes involved in mitochondrial function are higher in women than in men.

Nookaew Intawat I Svensson Per-Arne PA Jacobson Peter P Jernås Margareta M Taube Magdalena M Larsson Ingrid I Andersson-Assarsson Johanna C JC Sjöström Lars L Froguel Philippe P Walley Andrew A Nielsen Jens J Carlsson Lena M S LM

The Journal of clinical endocrinology and metabolism 20121221 2

<h4>Context</h4>Men and women differ in body fat distribution and adipose tissue metabolism as well as in obesity comorbidities and their response to obesity treatment.<h4>Objective</h4>The objective of the study was a search for sex differences in adipose tissue function.<h4>Design and setting</h4>This was an exploratory study performed at a university hospital.<h4>Participants and main outcome measures</h4>Resting metabolic rate (RMR), body composition, and sc adipose tissue genome-wide expres ...[more]

PMID: 23264395

Publication: 1/2

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Human subcutaneous adipose tissue and perithyroid adipose tissue gene expression

Project description:Different human adipose tissue depots may have functional differences. Subcutaneous human adipose tissue has been extensively studied, but less is known about other depots. Perithyroid (PT) adipose tissue contains not only white adipocytes but also brown adipocytes. The aim of this study was to compare the expression of brown adipocyte containing perithyroid adipose tissue with s.c. adipose tissue.role in the development of obesity. Expression profiling of adipose tissue may give insights into mechanisms contributing to obesity and obesity-related disorders.

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Gene expression data of brown-like adipocytes from Lgr4 homozygous mutant SVF

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