Ontology highlight
ABSTRACT:
ORGANISM(S): Sus scrofa
SUBMITTER: Diederik Kuster
PROVIDER: E-GEOD-27962 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kuster Diederik W D DW Merkus Daphne D Kremer Andreas A van Ijcken Wilfred F J WF de Beer Vincent J VJ Verhoeven Adrie J M AJ Duncker Dirk J DJ
Basic research in cardiology 20111105 6
Despite the apparent appropriateness of left ventricular (LV) remodeling following myocardial infarction (MI), it poses an independent risk factor for development of heart failure. There is a paucity of studies into the molecular mechanisms of LV remodeling in large animal species. We took an unbiased molecular approach to identify candidate transcription factors (TFs) mediating the genetic reprogramming involved in post-MI LV remodeling in swine. Left ventricular tissue was collected from remot ...[more]