EMT is the dominant program in human colon cancer
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Michael Nebozhyn
PROVIDER: E-GEOD-28814 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
EMT is the dominant program in human colon cancer.
Loboda Andre A Nebozhyn Michael V MV Watters James W JW Buser Carolyne A CA Shaw Peter Martin PM Huang Pearl S PS Van't Veer Laura L Tollenaar Rob A E M RA Jackson David B DB Agrawal Deepak D Dai Hongyue H Yeatman Timothy J TJ
BMC medical genomics 20110120
<h4>Background</h4>Colon cancer has been classically described by clinicopathologic features that permit the prediction of outcome only after surgical resection and staging.<h4>Methods</h4>We performed an unsupervised analysis of microarray data from 326 colon cancers to identify the first principal component (PC1) of the most variable set of genes. PC1 deciphered two primary, intrinsic molecular subtypes of colon cancer that predicted disease progression and recurrence.<h4>Results</h4>Here we r ...[more]
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