Juvenile and adult calvarial bone analysis
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: O Aalami
PROVIDER: E-GEOD-2896 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Differential transcriptional expression profiles of juvenile and adult calvarial bone.
Aalami Oliver O OO Nacamuli Randall P RP Salim Ali A Fong Kenton D KD Lenton Kelly A KA Song Hanjoon M HM Fang Tony D TD Longaker Michael T MT
Plastic and reconstructive surgery 20050601 7
<h4>Background</h4>It has widely been observed that young children are capable of reossifying large calvarial defects, while adults lack this endogenous tissue-engineering capacity. The ability of juvenile animals to regenerate calvarial defects has been investigated in multiple animal models, including mice. In this study, the authors used cDNA microarrays to investigate the expression of osteogenesis-associated genes upstream and downstream of Runx2 in juvenile and adult mouse calvaria.<h4>Met ...[more]
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