Unknown,Transcriptomics,Genomics,Proteomics

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MicorRNA expression in klotho-deficient and wild-type mouse brain subregions


ABSTRACT: The expression profiles of miRNAs in klotho-deficient and wild-type mouse brain subregions were examined. The data indicated that little or no marked difference in the miRNA expression was detected between them. Twelve samples prevared from 4- or 5-week-old klotho-deficient and wild-type mouse brain tissues (cerebrum, cerebellum and hippocampus) were examined.

ORGANISM(S): Mus musculus

SUBMITTER: Hirohiko Hohjoh 

PROVIDER: E-GEOD-29092 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Alteration of microRNA expression in the process of mouse brain growth.

Eda Akiko A   Takahashi Masaki M   Fukushima Tatsunobu T   Hohjoh Hirohiko H  

Gene 20110628 1


MicroRNAs (miRNAs) are a functional small non-coding RNA and play essential roles in gene regulation in development, differentiation and proliferation. In this study, we investigated expression profiles of miRNAs in the process of normal mouse brain growth from embryonic day 16.5 to ~19 months old by means of DNA microarray and reverse-transcription quantitative polymerase chain reaction, and we examined whether there was any association between the expression of miRNAs and brain growth. The res  ...[more]

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