Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Affymetrix gene expression array data for cardia and non-cardia gastric cancer samples

ABSTRACT: We identified different and common dysregulated genes in cardia and non-cardia gastric cancer in the two type of gastric cancer cardia and non-cardia gastric tumors and normal glands

ORGANISM(S): Homo sapiens

SUBMITTER: Howard Yang

PROVIDER: E-GEOD-29272 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Publications

Comparison of global gene expression of gastric cardia and noncardia cancers from a high-risk population in china.

Wang Gangshi G Hu Nan N Yang Howard H HH Wang Lemin L Su Hua H Wang Chaoyu C Clifford Robert R Dawsey Erica M EM Li Jian-Min JM Ding Ti T Han Xiao-You XY Giffen Carol C Goldstein Alisa M AM Taylor Philip R PR Lee Maxwell P MP

PloS one 20130522 5

<h4>Objective</h4>To profile RNA expression in gastric cancer by anatomic subsites as an initial step in identifying molecular subtypes and providing targets for early detection and therapy.<h4>Methods</h4>We performed transcriptome analysis using the Affymetrix GeneChip U133A in gastric cardia adenocarcinomas (n = 62) and gastric noncardia adenocarcinomas (n = 72) and their matched normal tissues from patients in Shanxi Province, and validated selected dysregulated genes with additional RNA stu ...[more]

PMID: 23717493

Similar Datasets

Affymetrix gene expression array data for cardia and non-cardia gastric cancer samples

Project description:We identified different and common dysregulated genes in cardia and non-cardia gastric cancer in the two type of gastric cancer

2013-07-19 | GSE29272 | GEO

Epigenome analysis of normal and gastric cardia cancer samples

Project description:Genome wide DNA methylation profiling of normal and gastric cardia cancer samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 850,000 CpGs in normal and gastric cardia cancer samples. Samples included 8 normal -gastrica cardia cancer paired tissues.

2023-01-01 | GSE200484 | GEO

Identification of gastric cancer associated serum antibodies using Helicobacter pylori antigen microarrays

Project description:Unbiased de-novo identification of biomarkers for H.pylori associated gastric cancer; Microarrays, representing 242 seroreactive H.pylori proteins, were generated by spotting of the respective gene constructs and cell-free on-chip expression. Antibody levels to these proteins were measured by application of sera from non-cardia gastric cancer patients and their matched controls. Possible new biomarkers, associated with gastric cancer, were evaluated by unadjusted conditional regression.

2020-09-14 | E-MTAB-9534 | biostudies-arrayexpress

Metabolite comparison of mouse gastric tissue and glands

Project description:The goal of this project was to compare the metabolite profiles of the: mouse gastric antrum and the mouse gastric corpus, the mouse gastric antrum and the mouse gastric antrum isolated glands, and the mouse gastric corpus and the mouse gastric corpus isolated glands.

2016-02-09 | ST000354 | MetabolomicsWorkbench

gene expression profiles of Barrett's esophagus, squamous esophagus and gastric cardia

Project description:SAGE performed on biopsies of Barrett's esophagus, squamous esophagus and gastric cardia taken from a metaplastic Barrett's esophagus patient. Keywords: SAGE comparative analysis of gene expression profiles of Barrett's esophagus, normal squamous esophagus and gastric cardia tissue

2005-06-20 | E-GEOD-2769 | biostudies-arrayexpress

RNA expression profiles in gastric cancer and tumor-adjacent normal tissues

Project description:This is a commercially available Affymetrix chip from 16 pairs of gastric cancer and corresponding adjacent normal tissues, used for screening differentially expressed genes associated with gastric cancer.

2021-03-25 | E-MTAB-9990 | biostudies-arrayexpress

A signature predicting poor prognosis in gastric and ovarian cancer represents a coordinated macrophage and stromal-response.

Project description:Genome wide mRNA expression profiling of 94 gastric tumours derived from Australian based cohort was performed. . From this data we identified a cluster of co-expressed genes termed the stromal response cluster which almost perfectly differentiates tumor from its non-malignant gastric tissue and hence can be regarded as a highly tumor-specific gene expression signature. We show that these genes are consistently co-expressed across a range of independent gastric datasets as well as other cancer types suggesting a conserved functional role in cancer. Profiling of 94 primary gastric tumors on Affymetrix GeneChip Human Genome U133 Plus 2.0 Arrays. All tumors were collected with approvals from Peter MacCallum Cancer Center, Australia; the Research Ethics Review Committee; and signed informed patient consent.

2014-04-01 | E-GEOD-51105 | biostudies-arrayexpress

Metabolomics Workbench ST000354 - GNPS - Metabolite comparison of mouse gastric tissue and glands

2018-08-02 | MSV000082700 | GNPS

gene expression profiles of Barrett's esophagus, squamous esophagus and gastric cardia

Project description:SAGE performed on biopsies of Barrett's esophagus, squamous esophagus and gastric cardia taken from a metaplastic Barrett's esophagus patient. Keywords: SAGE

2005-06-20 | GSE2769 | GEO

Global gene expression profiling and validation in esophageal squamous cell carcinoma (ESCC)

Project description:Esophageal squamous cell carcinoma (ESCC) is an aggressive tumor with poor prognosis. Understanding molecular changes in ESCC should improve identification of risk factors in molecular subtypes and provide potential targets for early detection and therapy. To better characterize molecular changes in ESCC, we followed up a previous cDNA array study with additional discovery and confirmatory studies in new ESCC cases using alternative methods. We profiled global gene expression (Affymetrix U133A/B chip) for discovery and confirmation, and validated selected dysregulated genes with additional RNA (qRT-PCR, N=51) or protein studies (immunohistochemistry [IHC] of tumor tissue microarray [TMA], N=275).We also found genes associated with survival. The dysregulated genes should aid in identifying risk factors in ESCC, as well as potential targets for early detection, and outcome prediction and therapy. 53 ESCC samples and 53 matched normal samples were analyzed (samples AE43 and AE45 were not run on HG-U133B due to not having enough material). Contributors have chosen not to include the clinical phenotypes in their GEO submission.

2010-09-01 | E-GEOD-23400 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data