Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Anagha Joshi
PROVIDER: E-GEOD-29515 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Tanaka Yosuke Y Joshi Anagha A Wilson Nicola K NK Kinston Sarah S Nishikawa Shinichi S Göttgens Berthold B
Developmental biology 20120421 2
Transcription factors have long been recognised as powerful regulators of mammalian development yet it is largely unknown how individual key regulators operate within wider regulatory networks. Here we have used a combination of global gene expression and chromatin-immunoprecipitation approaches during the early stages of haematopoietic development to define the transcriptional programme controlled by Runx1, an essential regulator of blood cell specification. Integrated analysis of these complem ...[more]