Unknown,Transcriptomics,Genomics,Proteomics

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The transcriptional program controlled by Runx1 during early hematopoietic development


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE29112: The transcriptional program controlled by Runx1 during early hematopoietic development (expression data) GSE29514: The transcriptional program controlled by Runx1 during early hematopoietic development (ChIP-seq data) Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Anagha Joshi 

PROVIDER: E-GEOD-29515 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

The transcriptional programme controlled by Runx1 during early embryonic blood development.

Tanaka Yosuke Y   Joshi Anagha A   Wilson Nicola K NK   Kinston Sarah S   Nishikawa Shinichi S   Göttgens Berthold B  

Developmental biology 20120421 2


Transcription factors have long been recognised as powerful regulators of mammalian development yet it is largely unknown how individual key regulators operate within wider regulatory networks. Here we have used a combination of global gene expression and chromatin-immunoprecipitation approaches during the early stages of haematopoietic development to define the transcriptional programme controlled by Runx1, an essential regulator of blood cell specification. Integrated analysis of these complem  ...[more]

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