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AEG-1 silencing induced gene expression alteration in glioma cells

ABSTRACT: This experiment is designed to evaluate gene expression alteration following AEG-1 (MTDH) silencing in glioma cells. AEG-1 is found to be a potential regulator through interaction with other transcription factor. We intended to investigate the enriched transcription factor dependent downstream gene sets regulated by AEG-1 form the differential expressed genes we obtained from AEG-1 silencing. Total RNA were extracted from U87MG glioma cells stably silencing AEG-1 and correspondent pSuper Retro vector cells respectively. Passage 5 of the indicated cells after infection and selection were harvested for RNA extraction.

ORGANISM(S): Homo sapiens

SUBMITTER: Mengfeng Li

PROVIDER: E-GEOD-29952 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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