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Gene expression analysis of mantle cell lymphoma (MCL) combined with laser microdissection

ABSTRACT: Wnt3 signaling pathway plays a central role in lymphomagenesis, and that specific mitotic regulators facilitate transformation into more aggressive forms. For initiation, we compared the tumor cells of MCL in situ (n=4) with normal mantle zone B-lymphocytes (n=4), which were selected by laser microdissection.For transformation, we selected the overlapping genes differentially expressed between both cMCL (n=4) vs aMCL (n=5) and classical vs aggressive areas in iMCL (n=2).

ORGANISM(S): Homo sapiens

SUBMITTER: Yoshizo Kimura

PROVIDER: E-GEOD-30189 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression analysis of mantle cell lymphoma (MCL) combined with laser microdissection

Project description:Wnt3 signaling pathway plays a central role in lymphomagenesis, and that specific mitotic regulators facilitate transformation into more aggressive forms.

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