Transcription profiling of w118 Drosophila melanogaster sampled at multiple developmental stages to dentifies genes that alter their expression in synchrony with the late third instar and prepupal pulses of 20
Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Robert Beckstead
PROVIDER: E-GEOD-3057 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis.
Beckstead Robert B RB Lam Geanette G Thummel Carl S CS
Genome biology 20051121 12
<h4>Background</h4>The steroid hormone 20-hydroxyecdysone (20E) triggers the major developmental transitions in Drosophila, including molting and metamorphosis, and provides a model system for defining the developmental and molecular mechanisms of steroid signaling. 20E acts via a heterodimer of two nuclear receptors, the ecdysone receptor (EcR) and Ultraspiracle, to directly regulate target gene transcription.<h4>Results</h4>Here we identify the genomic transcriptional response to 20E as well a ...[more]
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