Unknown,Transcriptomics,Genomics,Proteomics

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Expression data from Drosophila Btk29A mutant and revertant neuronal tissue


ABSTRACT: In Drosophila melanogaster, Btk29A displays a dynamic pattern of expression through the embryonic to adult stages. Complete loss-of function of both splice-forms is lethal, whereas selective absence of the type 2-form reduces the adult lifespan of the fly and causes male genitalial developmental abnormalities. Here, we investigated the role of Btk29A type 2 on a transcriptomic level in the larvae CNS and adult heads. We used samples either selectively defective in Btk29A type 2 (Btk29AficP) or flies were the Btk29A type 2 gene has been reintroduced (ficExc.1-16). Adult heads and larvae CNS were dissected for RNA extraction and hybridization on Affymetrix microarrays.

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Hossain Nawaz 

PROVIDER: E-GEOD-30627 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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