Short RNAs expression profiling in SET2 cells.
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Stefania Bortoluzzi
PROVIDER: E-GEOD-30672 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Characterization and discovery of novel miRNAs and moRNAs in JAK2V617F-mutated SET2 cells.
Bortoluzzi Stefania S Bisognin Andrea A Biasiolo Marta M Guglielmelli Paola P Biamonte Flavia F Norfo Ruggiero R Manfredini Rossella R Vannucchi Alessandro M AM
Blood 20120105 13
To gain insights into a possible role of microRNAs in myeloproliferative neoplasms, we performed short RNA massive sequencing and extensive bioinformatic analysis in the JAK2V617F-mutated SET2 cell line. Overall, 652 known mature miRNAs were detected, of which 21 were highly expressed, thus being responsible of most of miRNA-mediated gene repression. microRNA putative targets were enriched in specific signaling pathways, providing information about cell activities under massive posttranscription ...[more]
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