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Meis1 deficiency effect on thymic epithelial cells

ABSTRACT: Analysis of thymic epithelial cells lacking Meis1 gene using K14-CreERT2 Meis1fl/fl mice. Meis1 is a TALE class homeodomain transcription factor that critically regulates numerous embryonic developmental processes. Results provide insight into the role of Meis1 in the maintenance of postnatal thymic epithelial cells. Meis1-regulated gene expression in CD45- EpCAM+ mouse thymic epithelial cells was measured at 4 days after the induction of Meis1 deletion. Two independent experiments (pools of 6 mice; 2 pools per genotype) were performed.

ORGANISM(S): Mus musculus

SUBMITTER: Ryo Goitsuka

PROVIDER: E-GEOD-30824 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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