Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae S288c
SUBMITTER: Dana Huebert
PROVIDER: E-GEOD-30901 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Huebert Dana J DJ Kuan Pei-Fen PF Keleş Sündüz S Gasch Audrey P AP
Molecular and cellular biology 20120221 9
The response to stressful stimuli requires rapid, precise, and dynamic gene expression changes that must be coordinated across the genome. To gain insight into the temporal ordering of genome reorganization, we investigated dynamic relationships between changing nucleosome occupancy, transcription factor binding, and gene expression in Saccharomyces cerevisiae yeast responding to oxidative stress. We applied deep sequencing to nucleosomal DNA at six time points before and after hydrogen peroxide ...[more]