Chitin sensor
Ontology highlight
ABSTRACT:
ORGANISM(S): Vibrio cholerae
SUBMITTER: Karin Meibom
PROVIDER: E-GEOD-3103 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The Vibrio cholerae chitin utilization program.
Meibom Karin L KL Li Xibing B XB Nielsen Alex T AT Wu Cheng-Yen CY Roseman Saul S Schoolnik Gary K GK
Proceedings of the National Academy of Sciences of the United States of America 20040201 8
Chitin, an insoluble polymer of GlcNAc, is an abundant source of carbon, nitrogen, and energy for marine microorganisms. Microarray expression profiling and mutational studies of Vibrio cholerae growing on a natural chitin surface, or with the soluble chitin oligosaccharides (GlcNAc)(2-6), GlcNAc, or the glucosamine dimer (GlcN)2 identified three sets of differentially regulated genes. We show that (i) ChiS, a sensor histidine kinase, regulates expression of the (GlcNAc)(2-6) gene set, including ...[more]
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