Cis-Expression QTL Analysis of Established Risk Variants for Colorectal Cancer
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ABSTRACT: Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analyses to investigate possible regulatory functions on the expression of neighboring genes. Forty microsatellite stable and CpG island methylator phenotype-negative colorectal tumors and paired adjacent-normal colon tissues were used for genome-wide SNP and gene expression profiling in our cis-eQTL analyses. This submission represents transcriptome component of study.
ORGANISM(S): Homo sapiens
SUBMITTER: Lenora Loo
PROVIDER: E-GEOD-31737 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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