Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Diego Pasini
PROVIDER: E-GEOD-31786 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Vella Pietro P Barozzi Iros I Cuomo Alessandro A Bonaldi Tiziana T Pasini Diego D
Nucleic acids research 20111230 8
The Yin Yang 1 (YY1) transcription factor is a master regulator of development, essential for early embryogenesis and adult tissues formation. YY1 is the mammalian orthologue of Pleiohomeotic, one of the transcription factors that binds Polycomb DNA response elements in Drosophila melanogaster and mediates Polycomb group proteins (PcG) recruitment to DNA. Despite several publications pointing at YY1 having a similar role in mammalians, others showed features of YY1 that are not compatible with P ...[more]