Response of Saccharomyces cerevisiae to a rapid transfer from a fermentable to a nonfermentable carbon source.
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ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Peter Sarnow
PROVIDER: E-GEOD-3190 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Global and specific translational regulation in the genomic response of Saccharomyces cerevisiae to a rapid transfer from a fermentable to a nonfermentable carbon source.
Kuhn K M KM DeRisi J L JL Brown P O PO Sarnow P P
Molecular and cellular biology 20010201 3
The global gene expression program that accompanies the adaptation of Saccharomyces cerevisiae to an abrupt transfer from a fermentable to a nonfermentable carbon source was characterized by using a cDNA microarray to monitor the relative abundances and polysomal distributions of mRNAs. Features of the program included a transient reduction in global translational activity and a severe decrease in polysome size of transcripts encoding ribosomal proteins. While the overall translation initiation ...[more]
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