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Homeostatic Adjustment and Metabolic Remodeling in Glucose-limited Yeast Cultures Time Course 2


ABSTRACT: Time course of batch growth. Reference (channel 1) was a culture grown in MD medium with 2.4 g/L glucose, with 5 slpm air-flow, stirring at 400 rpm and a constant 300C temperature, dilution 0.25 volumes/hour. The experimental (channel 2) samples were grown in batch for the indicated time. Groups of assays that are related as part of a time series. FactorCategory: Elapsed Time; name: Elapsed Time; Measurement: time(absolute) 6 h; name: 34357_Elapsed Time; Measurement: time(absolute) 10.5 h; name: 34365_Elapsed Time; Measurement: time(absolute) 8 h; name: 34358_Elapsed Time; Measurement: time(absolute) 9 h; name: 34359_Elapsed Time; Measurement: time(absolute) 11 h; name: 34368_Elapsed Time; Measurement: time(absolute) 9.5 h; name: 34360_Elapsed Time; Measurement: time(absolute) 10 h; name: 34362_Elapsed Time Computed

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Matt Brauer 

PROVIDER: E-GEOD-3206 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Homeostatic adjustment and metabolic remodeling in glucose-limited yeast cultures.

Brauer Matthew J MJ   Saldanha Alok J AJ   Dolinski Kara K   Botstein David D  

Molecular biology of the cell 20050309 5


We studied the physiological response to glucose limitation in batch and steady-state (chemostat) cultures of Saccharomyces cerevisiae by following global patterns of gene expression. Glucose-limited batch cultures of yeast go through two sequential exponential growth phases, beginning with a largely fermentative phase, followed by an essentially completely aerobic use of residual glucose and evolved ethanol. Judging from the patterns of gene expression, the state of the cells growing at steady  ...[more]

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