Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

MicroRNA expression in peripheral blood predicts poor and prolonged response to sunitinib.


ABSTRACT: Peripheral blood samples were taken before initiation of therapy and 2 weeks later from patients with advanced renal cell carcinoma treated with sunitinib in first line. MicroRNA expression in peripheral blood was assessed using microarrays and several models predicting poor response and prolonged response to sunitinib were constructed and evaluated. Peripheral blood samples obtained before initiation of therapy with sunitinib and 14 days later were used to assess expression values of miRNAs.

ORGANISM(S): Homo sapiens

SUBMITTER: Juan M-CM-^Angel Fresno Vara 

PROVIDER: E-GEOD-32099 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications


Anti-angiogenic therapy benefits many patients with advanced renal cell carcinoma (RCC), but there is still a need for predictive markers that help in selecting the best therapy for individual patients. MicroRNAs (miRNAs) regulate cancer cell behavior and may be attractive biomarkers for prognosis and prediction of response. Forty-four patients with RCC were recruited into this observational prospective study conducted in nine Spanish institutions. Peripheral blood samples were taken before init  ...[more]

Similar Datasets

2013-02-11 | GSE32099 | GEO
2015-06-26 | GSE70282 | GEO
2015-06-26 | E-GEOD-70282 | biostudies-arrayexpress
2021-11-03 | PXD027065 | Pride
2015-05-25 | E-GEOD-67818 | biostudies-arrayexpress
2015-05-25 | GSE67818 | GEO
2024-04-17 | GSE216494 | GEO
2021-12-03 | GSE189331 | GEO
2023-03-31 | GSE226245 | GEO
2016-09-30 | GSE69535 | GEO