Expression data from early Zebrafish embryos after knockdown of mir-34
Ontology highlight
ABSTRACT:
ORGANISM(S): Danio rerio
SUBMITTER: Kartik Soni
PROVIDER: E-GEOD-32360 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
miR-34 is maternally inherited in Drosophila melanogaster and Danio rerio.
Soni Kartik K Choudhary Ashwani A Patowary Ashok A Singh Angom Ramcharan AR Bhatia Shipra S Sivasubbu Sridhar S Chandrasekaran Shanti S Pillai Beena B
Nucleic acids research 20130306 8
MicroRNAs (miRNAs) are small, endogenous, regulatory RNA molecules that can bind to partially complementary regions on target messenger RNAs and impede their expression or translation. We rationalized that miRNAs, being localized to the cytoplasm, will be maternally inherited during fertilization and may play a role in early development. Although Dicer is known to be essential for the transition from single-celled zygote to two-cell embryo, a direct role for miRNAs has not yet been demonstrated. ...[more]
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