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Expression data from active CD4 T cells

ABSTRACT: miR-17 from the miR-17-92 cluster regulate activation-induced cell death in T cells and modulate inducible regulatory T cell differentiation. We used microarrays to detail the global program of gene expression modulated by miR-17 and aim to identify the potential targets of miR-17. CD4 T cells from wild type or miR-17-92 deficient mice were activated and transduced with empty vector or that overexpressing miR-17. Potential targets of miR-17 should be upregulated in miR-17-92 deficient CD4 T cells compared to wild type CD4 T cells, and downregulated when miR-17 were reintroduced into the miR-17-92 deficient T cells.

ORGANISM(S): Mus musculus

SUBMITTER: Feng Feng

PROVIDER: E-GEOD-32533 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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