MRNA decay in E. coli
Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli
SUBMITTER: Jon Bernstein
PROVIDER: E-GEOD-3267 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays.
Bernstein Jonathan A JA Khodursky Arkady B AB Lin Pei-Hsun PH Lin-Chao Sue S Cohen Stanley N SN
Proceedings of the National Academy of Sciences of the United States of America 20020715 15
Much of the information available about factors that affect mRNA decay in Escherichia coli, and by inference in other bacteria, has been gleaned from study of less than 25 of the approximately 4,300 predicted E. coli messages. To investigate these factors more broadly, we examined the half-lives and steady-state abundance of known and predicted E. coli mRNAs at single-gene resolution by using two-color fluorescent DNA microarrays. An rRNA-based strategy for normalization of microarray data was d ...[more]
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