Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: HORVAT Branka
PROVIDER: E-GEOD-32902 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Mathieu Cyrille C Guillaume Vanessa V Sabine Amélie A Ong Kien Chai KC Wong Kum Thong KT Legras-Lachuer Catherine C Horvat Branka B
PloS one 20120229 2
Nipah virus (NiV) is a recently emerged zoonotic Paramyxovirus that causes regular outbreaks in East Asia with mortality rate exceeding 75%. Major cellular targets of NiV infection are endothelial cells and neurons. To better understand virus-host interaction, we analyzed the transcriptome profile of NiV infection in primary human umbilical vein endothelial cells. We further assessed some of the obtained results by in vitro and in vivo methods in a hamster model and in brain samples from NiV-inf ...[more]