Unknown,Transcriptomics,Genomics,Proteomics

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Expression data from gastric tissues: Cancer Samples vs. Matched Adjacent Noncancerous Samples


ABSTRACT: To elucidate gene expression associated with copy number changes, we performed a genome-wide copy number and expression microarray analysis of 25 pairs of gastric tissues. 25 pairs of gastric tissues: gastric cancer tissues vs. matched adjacent noncancerous tissues.

ORGANISM(S): Homo sapiens

SUBMITTER: Cheng Lei 

PROVIDER: E-GEOD-33335 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Identification of genes with a correlation between copy number and expression in gastric cancer.

Cheng Lei L   Cheng Lei L   Wang Ping P   Yang Sheng S   Yang Yanqing Y   Zhang Qing Q   Zhang Wen W   Xiao Huasheng H   Gao Hengjun H   Zhang Qinghua Q  

BMC medical genomics 20120504


<h4>Background</h4>To elucidate gene expression associated with copy number changes, we performed a genome-wide copy number and expression microarray analysis of 25 pairs of gastric tissues.<h4>Methods</h4>We applied laser capture microdissection (LCM) to obtain samples for microarray experiments and profiled DNA copy number and gene expression using 244K CGH Microarray and Human Exon 1.0 ST Microarray.<h4>Results</h4>Obviously, gain at 8q was detected at the highest frequency (70%) and 20q at t  ...[more]

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