Diversity of gene expression in adenocarcinoma of the lung.
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER:
PROVIDER: E-GEOD-3398 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Diversity of gene expression in adenocarcinoma of the lung.
Garber M E ME Troyanskaya O G OG Schluens K K Petersen S S Thaesler Z Z Pacyna-Gengelbach M M van de Rijn M M Rosen G D GD Perou C M CM Whyte R I RI Altman R B RB Brown P O PO Botstein D D Petersen I I
Proceedings of the National Academy of Sciences of the United States of America 20011113 24
The global gene expression profiles for 67 human lung tumors representing 56 patients were examined by using 24,000-element cDNA microarrays. Subdivision of the tumors based on gene expression patterns faithfully recapitulated morphological classification of the tumors into squamous, large cell, small cell, and adenocarcinoma. The gene expression patterns made possible the subclassification of adenocarcinoma into subgroups that correlated with the degree of tumor differentiation as well as patie ...[more]
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