Transcriptional profile of PBMCs in patients with acute RSV or Influenza infection

ABSTRACT: To study the transcriptional profile of patients with acute RSV or Influenza infection,children of median age 2.4 months (range 1.5-8.6) hospitalized with acute RSV and influenza virus infection were offered study enrollment after microbiologic confirmation of the diagnosis. Blood samples were collected from them within 42-72 hours of hospitalization. We excluded children with suspected or proven polymicrobial infections, with underlying chronic medical conditions (i.e congenital heart disease, renal insufficiency), with immunodeficiency, or those who received systemic steroids or other immunomodulatory therapies. The RSV cohort consisted of 51 patients with median age of 2 months (range 1.5-3.9) and the influenza cohort had 28 patients with median age of 5.5 months (range 1.4-21). Con

ORGANISM(S): Homo sapiens

SUBMITTER: Damien Chaussabel 

PROVIDER: E-GEOD-34205 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress