Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Expression data from 3 gamma-secretase or mock-treated mantle cell lymphoma (MCL) cell lines


ABSTRACT: We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition of the NOTCH pathway by gamma-secretase inhibition. The aim of this study was to identify transcriptional targets of NOTCH signaling in MCL. 3 MCL cell lines (Mino, Rec-1, SP-49 treated with Mock or 1 micromolar compound E for 24 hours, in duplicate.

ORGANISM(S): Homo sapiens

SUBMITTER: Robert Kridel 

PROVIDER: E-GEOD-34602 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2011-12-22 | GSE34602 | GEO
2013-12-01 | E-GEOD-52434 | biostudies-arrayexpress
2013-12-01 | GSE52434 | GEO
2014-08-31 | E-GEOD-57128 | biostudies-arrayexpress
| PRJNA912113 | ENA
2019-09-13 | E-MTAB-7866 | biostudies-arrayexpress
2013-12-01 | GSE52435 | GEO
2013-12-01 | E-GEOD-52435 | biostudies-arrayexpress
2013-12-01 | E-GEOD-42549 | biostudies-arrayexpress
2013-12-01 | GSE42549 | GEO