Expression data from 3 gamma-secretase or mock-treated mantle cell lymphoma (MCL) cell lines
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ABSTRACT: We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition of the NOTCH pathway by gamma-secretase inhibition. The aim of this study was to identify transcriptional targets of NOTCH signaling in MCL.
ORGANISM(S): Homo sapiens
PROVIDER: GSE34602 | GEO | 2011/12/22
SECONDARY ACCESSION(S): PRJNA150467
REPOSITORIES: GEO
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