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Transcriptional profile of EHEC 86-24 fusK (HK) and fusR (RR) mutants

ABSTRACT: The goals of this experiment was to obtain a transcriptional profile of EHEC 86-24 upon deletion of fusK or fusR genes. The samples were grown in DMEM until late logaritmic phase then RNA was extracted using the TriZol method.

ORGANISM(S): Escherichia coli O157:H7

SUBMITTER: Alline Pacheco

PROVIDER: E-GEOD-34991 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Fucose sensing regulates bacterial intestinal colonization.

Pacheco Alline R AR Curtis Meredith M MM Ritchie Jennifer M JM Munera Diana D Waldor Matthew K MK Moreira Cristiano G CG Sperandio Vanessa V

Nature 20121118 7427

The mammalian gastrointestinal tract provides a complex and competitive environment for the microbiota. Successful colonization by pathogens requires scavenging nutrients, sensing chemical signals, competing with the resident bacteria and precisely regulating the expression of virulence genes. The gastrointestinal pathogen enterohaemorrhagic Escherichia coli (EHEC) relies on inter-kingdom chemical sensing systems to regulate virulence gene expression. Here we show that these systems control the ...[more]

PMID: 23160491

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Hfq virulence regulation in enterohemorhagic Escherichia coli O157:H7 strain 86-24

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2013-01-08 | E-GEOD-43325 | biostudies-arrayexpress

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Project description:A study on the effects of an sdiA mutant and the AHL molecule on the virulence of EHEC Comparison of wild type E. coli 8624 with and without AHL to and E. coli 8624 sdiA mutant with and without AHL to determine the effects of each factor on gene expression

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