Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptional profile of EHEC 86-24 fusK (HK) and fusR (RR) mutants


ABSTRACT: The goals of this experiment was to obtain a transcriptional profile of EHEC 86-24 upon deletion of fusK or fusR genes. The samples were grown in DMEM until late logaritmic phase then RNA was extracted using the TriZol method.

ORGANISM(S): Escherichia coli O157:H7

SUBMITTER: Alline Pacheco 

PROVIDER: E-GEOD-34991 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


The mammalian gastrointestinal tract provides a complex and competitive environment for the microbiota. Successful colonization by pathogens requires scavenging nutrients, sensing chemical signals, competing with the resident bacteria and precisely regulating the expression of virulence genes. The gastrointestinal pathogen enterohaemorrhagic Escherichia coli (EHEC) relies on inter-kingdom chemical sensing systems to regulate virulence gene expression. Here we show that these systems control the  ...[more]

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