Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli O157:H7
SUBMITTER: Alline Pacheco
PROVIDER: E-GEOD-34991 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Pacheco Alline R AR Curtis Meredith M MM Ritchie Jennifer M JM Munera Diana D Waldor Matthew K MK Moreira Cristiano G CG Sperandio Vanessa V
Nature 20121118 7427
The mammalian gastrointestinal tract provides a complex and competitive environment for the microbiota. Successful colonization by pathogens requires scavenging nutrients, sensing chemical signals, competing with the resident bacteria and precisely regulating the expression of virulence genes. The gastrointestinal pathogen enterohaemorrhagic Escherichia coli (EHEC) relies on inter-kingdom chemical sensing systems to regulate virulence gene expression. Here we show that these systems control the ...[more]