Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Susan Quirk
PROVIDER: E-GEOD-35123 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Biology of reproduction 20120607 6
The hedgehog (HH) signaling pathway is critical for ovarian function in Drosophila, but its role in the mammalian ovary has not been defined. Previously, expression of a dominant active allele of the HH signal transducer protein smoothened (SMO) in Amhr2(cre/+)SmoM2 mice caused anovulation in association with a lack of smooth muscle in the theca of developing follicles. The current study examined events during the first 2 wk of life in Amhr2(cre/+)SmoM2 mice to gain insight into the cause of ano ...[more]