Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Joseph Hacia
PROVIDER: E-GEOD-35357 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Development (Cambridge, England) 20120321 9
The tongue is a muscular organ and plays a crucial role in speech, deglutition and taste. Despite the important physiological functions of the tongue, little is known about the regulatory mechanisms of tongue muscle development. TGFβ family members play important roles in regulating myogenesis, but the functional significance of Smad-dependent TGFβ signaling in regulating tongue skeletal muscle development remains unclear. In this study, we have investigated Smad4-mediated TGFβ signaling in the ...[more]