Ontology highlight
ABSTRACT:
ORGANISM(S): Mustela putorius furo
SUBMITTER: Longsi Ran
PROVIDER: E-GEOD-36019 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
León Alberto J AJ Banner David D Xu Luoling L Ran Longsi L Peng Zhiyu Z Yi Kang K Chen Chao C Xu Fengping F Huang Jinrong J Zhao Zhen Z Lin Zhen Z Huang Stephen H S SH Fang Yuan Y Kelvin Alyson A AA Ross Ted M TM Farooqui Amber A Kelvin David J DJ
Journal of virology 20121212 4
Ferrets have become an indispensable tool in the understanding of influenza virus virulence and pathogenesis. Furthermore, ferrets are the preferred preclinical model for influenza vaccine and therapeutic testing. Here we characterized the influenza infectome during the different stages of the infectious process in ferrets with and without prior specific immunity to influenza. RNA from lung tissue and lymph nodes from infected and naïve animals was subjected to next-generation sequencing, follow ...[more]