Transcriptomics

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Gene expression profiles in lymph nodes from ferrets infected with A/California/07/2009


ABSTRACT: Pandemic H1N1 influenza A Human infection leads to symptoms ranging from mild to severe with lower respiratory complications observed in a small but significant number of infected individuals. Microarray analysis of the lymph nodes from ferrets infected with A/California/07/2009 shows intense gene upregulation during days 3 and 5 post-infection, and followed by marked downregulation during days 7 and 14 post infection. Gene expression profiles during the upregulation phase show intense chemokine activity, cell replication and activation of the lymphocyte-related signaling pathways.

ORGANISM(S): Mustela putorius furo Canis lupus familiaris

PROVIDER: GSE36019 | GEO | 2013/01/28

SECONDARY ACCESSION(S): PRJNA151609

REPOSITORIES: GEO

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