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Transcription profiling of human vastus lateralis biopsies from healthy young (20-29 years old) or older (65-75 years old) adults

ABSTRACT: vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old)

ORGANISM(S): Homo sapiens

SUBMITTER: Stephen Welle

PROVIDER: E-GEOD-362 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profile of aging in human muscle.

Welle Stephen S Brooks Andrew I AI Delehanty Joseph M JM Needler Nancy N Thornton Charles A CA

Physiological genomics 20030707 2

Studies of gene expression related to aging of skeletal muscle have included few subjects or a limited number of genes. We conducted the present study to produce more comprehensive gene expression profiles. RNA was extracted from vastus lateralis biopsies obtained from healthy young (21-27 yr old, n = 8) and older men (67-75 yr old, n = 8) and was analyzed with high-density oligonucleotide arrays. Of the approximately 44,000 probe sets on the arrays, approximately 18,000 yielded adequate signals ...[more]

PMID: 12783983

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